簡(jiǎn)介:DMAT是一種有效的,特異性的 CK2 抑制劑,IC50 值為 130 nM。
DMAT物理化學(xué)性質(zhì):
分子式 |
C9H7Br4N3 |
分子量 |
476.788 |
精確質(zhì)量 |
472.737 |
PSA |
31.92 |
LogP |
4.6789 |
儲(chǔ)存條件 |
2-8℃ |
DMAT詳細(xì)介紹:
產(chǎn)品名稱: |
[Perfemiker]DMAT,≥98% |
中文別名: |
2-二甲基氨基-4,5,6,7-四溴苯并咪唑 |
英文名稱: |
DMAT |
英文別名: |
4,5,6,7-tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine;1H-Benzimidazol-2-amine, 4,5,6,7-tetrabromo-N,N-dimethyl-;DMAT;Casein kinase II Inhibitor;CK2 Inhibitor;2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole;4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzo[d]imidazol-2-amine;CK2 Inhibitor II;ck2inhibitor;CK2 Inhibitor II, DMAT;DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE;Casein Kinase II Inhibitor II, DMAT;InSolution? Casein Kinase II Inhibitor, DMAT;1zoe;K25;CK2 Inhibitor 2;DMAT(CK2 Inhibitor);C9H7br4N3;GTPL9323 |
品牌: |
Perfemiker |
CAS號(hào): |
749234-11-5 |
分子式: |
C9N3BR4H7 |
分子量: |
476.79 |
純度: |
≥98% |
詳細(xì)描述: |
博飛美科提供的DMAT,≥98%為博飛美科出品的酶抑制劑,產(chǎn)品穩(wěn)定,定制速度快,極大地方便了廣大科研客戶的使用需求。查詢關(guān)鍵詞:酶抑制劑,749234-11-5,DMAT,≥98%,DMAT,博飛美科,Perfemiker,上海,廠家現(xiàn)貨。 |
DMAT參考文獻(xiàn):
[1]. Yde CW, et al. Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitorDMAT. Cancer Lett. 2007 Oct 28;256(2):229-37.
[2]. Lawnicka H, et al. Anti-neoplastic effect of protein kinase CK2 inhibitor, 2-dimethylamino-4,5,6,7-tetrabromobenzimidazole (DMAT), on growth and hormonal activity of human adrenocortical carcinoma cell line (H295R) in vitro. Cell Tissue Res. 2010 May;340(
[3]. Pagano MA, et al. The selectivity of inhibitors of protein kinase CK2: an update. Biochem J. 2008 Nov 1;415(3):353-65.
[4]. Sass G, et al. Inhibition of experimental HCC growth in mice by use of the kinase inhibitor DMAT. Int J Oncol. 2011 Aug;39(2):433-42.
產(chǎn)品技術(shù)規(guī)格說明書由上海創(chuàng)賽科技有限公司收集整理,僅作參考使用。